Endocrine Abstracts

Obesity epidemic is one of the major concerns in the world. Worryingly, a high percentage of pregnant women have obesity, which could imply several consequences. Maternal obesity leads to different abnormalities in pregnancy and delivery. In addition, recent studies show that the offspring of obese mothers has an increased probability to suffer cardiovascular, metabolic and reproductive diseases. We have previously demonstrated that exposure to a high fat diet is related to ob...

Obesity during gestation has been related to predisposition to endocrine and metabolic diseases in the offspring. Regarding reproductive effects, an increase in BMI in pregnant mothers is associated with precocious puberty in their offspring. This has been replicated in animal models of high fat diet (HFD) administration to mothers. Also, gestational obesity has been associated to higher susceptibility to developing breast cancer in the offspring. As both precocious puberty an...